Biostimulator
- SPARK IDEA

- May 27
- 5 min read
Updated: Jun 16

What is a biostimulator?
Biostimulator is an injectable substance designed to stimulate the body to produce collagen and
Natural elastin, an important protein that keeps skin elastic, firm and youthful, is why using Biostimulator is an innovation that helps restore skin from the inside out, giving more natural and longer-lasting results than conventional fillers.
How does Biostimulator work?

When Biostimulator is injected under the skin, it acts as a "stimulator" for the fibroblast cells, which are the main cells in the production of collagen and elastin, to work more efficiently. This results in the continuous production of new collagen and elastin, resulting in a stronger skin structure, firmer skin, reduced wrinkles and a noticeable improvement in overall skin quality.
Advantages of Biostimulator
Natural results: Stimulates the production of its own collagen, resulting in a naturally plump skin that doesn’t look hard or lumpy.
Long-lasting results: Since it stimulates the production of new collagen, the results last longer than traditional fillers, possibly lasting 1-2 years or more, depending on the type of Biostimulator and maintenance.
Improves overall skin quality: In addition to firming, it also helps to make the skin smoother, tighten pores, and look healthier.
Safety: Most biostimulators used are biocompatible and biodegradable.
Popular Biostimulators: Which One Is Right For You?
Biostimulator is an injectable substance that stimulates the body's natural production of collagen and elastin, allowing the skin to heal from the inside out. The results are therefore natural and long-lasting. Currently, there are many types of Biostimulator, each with different components, mechanisms of action, and strengths, so you can choose the one that is most suitable for your skin problems and needs.
1. Sculptra

Main components: Poly-L-Lactic Acid (PLLA)
Mechanism of operation
PLLA It is a substance that is compatible with the body and will gradually break down over a period of time, but during that time, it stimulates the fibroblast cells to continuously and in large quantities produce new collagen, which helps restore volume and a strong skin structure.
Highlights
Restore natural volume: Suitable for those who want to restore volume lost due to aging, such as sunken cheeks, sunken temples, or those who want to adjust the shape of the face to look naturally fuller.
Long-lasting results: Results can last up to 2 years or more as it stimulates the body's own collagen production.
Gradual: Results become more apparent over 2-3 months after injection, making it look natural and no one will notice “what have you done?”
Suitable for: Those who have sagging skin, deep wrinkles, sunken faces, lack of volume, or those who want long-lasting and natural-looking results.
2. Juvelook

Main ingredients: Poly D,L-Lactic Acid (PDLLA) mixed with Hyaluronic Acid (HA)
Mechanism of operation
It is a Hybrid Biostimulator with two mechanisms in one. HA helps to moisturize and provide initial filling results. PDLLA gradually breaks down and stimulates long-term collagen production.
Highlights
Focus on improving skin quality: It excels in helping to tighten pores, reduce acne scars, smooth and refine skin, and increase moisture.
Immediate and long-term results: HA provides immediate hydration and plumping results, while PDLLA stimulates collagen for long-term results.
Suitable for sensitive skin: Can be used on sensitive areas such as under the eyes to help reduce wrinkles and dark circles.
Suitable for: People with large pores, shallow acne scars, dry and dehydrated skin, fine lines, or those who want to restore their skin quality to be smoother and brighter.
3.Radiesse

Main Ingredients: Calcium Hydroxylapatite (CaHA) Microspheres
Mechanism of operation
CaHA is a small particle that is similar to bone mineral. When injected, it acts as a temporary support structure and stimulates the production of Type I and Type III collagen, as well as elastin, which makes the skin strong and elastic.
Highlights
Instant volume + Collagen stimulation : It has outstanding properties that provide immediate volume after injection and continuously stimulate collagen production.
Solve deep wrinkles: It is highly effective in filling deep wrinkles such as the nasolabial folds, mouth corner folds, and lifting the facial frame.
Versatile areas : Can be used on the face (except under the eyes and lips), neck and back of the hands to reduce wrinkles and increase fullness.
Suitable for: Those with moderate to severe wrinkles, moderate sagging skin, those who want to refine the facial contours, or those who want to rejuvenate the skin on the neck and back of the hands.
4.Profhilo

Main components: High and Low Molecular Weight Hyaluronic Acid (HA) with high purity.
Mechanism of operation
Profhilo is a bio-remodeling agent with a high concentration of HA that is distributed throughout the dermis, stimulating skin cells to produce collagen and elastin, and improving overall skin quality.
Highlights
Focus on improving skin quality and increasing moisture: It is not a filler-like volume filling, but rather focuses on making the skin moist, plump, elastic, and firm from within.
Spot injection technique (BAP Technique) : Usually injects only 5 points per side of the face to allow the substance to spread evenly, making it convenient and reducing needle marks.
Reduce skin problems "Crepey Skin" : Suitable for skin that looks wrinkled, wrinkled, like wrinkled paper, especially on the face, neck and back of the hands.
Suitable for: Those who want to improve their overall skin quality, make it more hydrated, firmer and more elastic, have fine lines, or skin that is starting to look dull and lackluster.
Preparation before Biostimulator
Consult a medical professional to assess your skin condition and suitability.
Inform us of any history of drug allergies, chronic diseases, medications you are currently taking, or dietary supplements you are taking.
Avoid taking certain medications, such as aspirin, NSAIDs (non-steroidal anti-inflammatory drugs)
Steroids, vitamins, and certain supplements that may affect blood clotting should be avoided at least 1-2 weeks prior to the procedure (as advised by your doctor).
Avoid drinking alcohol at least 24-48 hours before the procedure.
Get enough rest before the procedure.
Biostimulator post-care
Cold compresses: During the first 24-48 hours, cold compresses may be applied to reduce any swelling or bruising that may occur.
Avoid vigorous touching or massaging: Avoid pressing, massaging, or rubbing the injection area vigorously for the first 1-2 days.
Massage (in some cases): Your doctor may recommend a special massage technique for the injection site to help distribute the substance well and stimulate collagen production (depending on the type of Biostimulator).
Avoid high heat: Avoid sauna, steam, laser, or activities that cause high heat in the injection area for the first 1-2 weeks.
Avoid strenuous exercise: Avoid strenuous exercise for the first 24-48 hours.
Drink enough water: It helps your body process to function efficiently.
Follow-up appointments: Return to your doctor for follow-up appointments to monitor your treatment results and assess your progress.









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